Following are the OSPE papers (Set-5) of 4th year MBBS Special Pathology UHS with Answers/Keys.
2.UC involve rectum , sigmoid n may involve entire colon
1. Myocardial Infarct
2. factors: occlusion of an artery (atherosclerosis) , thrombosis, embolus, smoking, age, sex, etc
3. At 5hrs-early coagulative necrosis, edema, hemorrhage
2- atherosclerotic plaque penetrate the intramycardial branches of coronary arteries n severe occlusion leads mycordial injury. 3- it composed of cells inlude SMCs, macrophages n Tcells . ECM include collagen , elastic fiber n proteoglycans, Intracellular n extracellular lipids . Superficial layer is Fibrous cap n deep to it is necrotic core
1. Paget cells which are highly eosionphilic
2. DCIS, Invasive ductul carcinoma3. Hergulin produced by keritanocytes act on cancer cells and they convert iinto paget cells, these paget cells go to the skin withut disrupting the basement membrane , disrupt the epitheilum and hence edema and oozing occurs
2.Immunofluorescence staining3.three types : Minimal change, rapid progressive n membranous
1 ) -single layer of Tall columnar epithelium , they are ciliated n some part are dome shaped secretary cells .
- Psommoma bodies 2) Serous type
3) Mucinous n endometroid
1- seminoma cells : large , round to polyhydral cells wth distinct cell membranes , clear cytoplasm n central round nuclei with infrequent mitosis
2- Seminoma 3- Non differentiated totipotential germ cell tumor
1- Disruption of thyroid follicles , with extravasation of colloid leading to a PMN infiltrate.
2- subacute granulomatous thyroiditis 3- viral infection
1- Gaint cell tumor of bone
2- benign
3- Soap bubble appearence. 2- benign
4-Reactive macrophages n mononuclear celss
1-honeycomb appearence
2- Interstitial pneumonia, non-specific interstitial pneumonia, pneumoconiosis 3-Interstitium
3. erythropoitin level will b low
1.less than 3.5 gm/day urinary protien in nephritic syndrome
2. hyperlipidemia, hypoalbuminemia, lipiduria, oedema, protienuria
3. low but not as low as in nephrotic syndrome
1. Grave's Diesease
2. TSH
1. Papillary carcinoma of thyroid gland
2. Multifocal, cystic and contain papillary excresences
3. Formalin
1. ALL
2. Giemsa3. sudan black stain.
4. condensed nuclear chromatin, small nucleoli, agranular scant cytoplasm
2. Mass attached to dura and indenting brain, m/e will show psammoma bodies and cells in whorls
3. Meningiothelial cells of arachnoid
1. Peptic ulcer
2. hemorrhage, perforation
3. Zollinger Ellison syndrome
16 COMMENTS:
great job.. but Dear plz correct sm mistake on station 12.. Giant cell tumor is BENIGN not malignant and on radiograph u will find SOAP BUBBLE APPEARENCE
Gr8 work.....JAZAKALLAH...
GOD BLESS U.....
station 2 zollinger elison syndrome
Thanks Alot bro...Always helping..God bless U :)
bro station 18 [er i think its hashimoto...us mae thyroglobulin autoantibodies hoti hain please check and confirm...
tachycardia and exophthalmos are typical of graves...
in ALL u do PAS nt sudan black (station 20) plz correct it
Hammad ur rehman
isn't station 1 (the very first one)Crohn's? the lesions appear to be skip lesions.
this link says that the lesion on station 7 is membranous no MPGN.
http://library.med.utah.edu/WebPath/RENAHTML/RENAL088.html
Allah Bless u
giant cell tumor is benign but locally malignant
that is locally invasive. but we still consider it benign overall
unobserved station 9......'non differentiated totipotential germ cell tumors' is "embryonal carcinoma" not 'seminoma'..............therefore it belongs to "seminomatous germ cell tumors" category...
if colon is invlove then there is involved it is more chances of ulcerative colitis .
antithyroglobulin and anti microsomal antibodies are also found in graves disease (ref.goljan) :)
Its Hashimotos Thyroiditis.
beginning of the disease shows signs of HYPERthyroidism due to follicular rupture.
Kindly Correct it.
And Thank you for the Material.
JazakAllah
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